LEAP | Long-Acting/Extended Release Antiretroviral Resource Program

Funded by an R24 grant from the National Institutes of Health, the mission of LEAP is 3-fold:

To support scientific innovation related to the development of LA/ER antiretroviral drugs through investigator access to broad-based scientific expertise, including the pharmaceutical industry.
To develop a communications and data hub to support investigators in this field
To provide a Modeling and Simulation Core Service that helps investigators identify the most promising approaches to the development of new products.

LEAP endeavors to serve as a central communications hub/data repository for investigators developing LA/ER treatment for HIV and TB. What information or assistance are you looking for?

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Finding funds for research can be a challenge. The following resources are provided to help guide your efforts in seeking potential funding streams for your work. We will update this section as new opportunities are released.

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A major role of LEAP is to provide researchers centralized access to relevant scholarly materials, data, and publication from ongoing laboratory and clinical research that catalog progress in the field.

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Physiologically-based pharmacokinetic (PBPK) modelling and simulation of drug concentrations for LA ARV formulations can guide selection of dose, regimen, and formulation. A state-of-the-art Modeling and Simulation Core is a pivotal service offered to investigators working on preclinical and clinical development of LA/ER ARV by LEAP.

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